4 ms·

Thanks for the article, looks like that one is from 2016. I'll share another article I found with a quick search -- "Saturated fat is more metabolically harmful

Thanks for the article, looks like that one is from 2016. I'll share another article I found with a quick search -- "Saturated fat is more metabolically harmful for the human liver than unsaturated fat or simple sugars" : https://pubmed.ncbi.nlm.nih.gov/29844096/ https://pubmed.ncbi.nlm.nih.gov/29844096/ Now I'm not so sure which is the "primary driver". There are quite a few competing thoughts but maybe the point is you should lower both. That's probably one reason many docs (including mine in the past) recommend cutting both.

joecool1029 4y ago
> Now I'm not so sure which is the "primary driver". There are quite a few competing thoughts but maybe the point is you should lower both. On that I don't think we disagree. However, saturated fat on its own isn't super palatable. There was a community I discovered a few years ago deliberately trying to up their saturated fat intake (specifically steric acid) and on it's own it's about as pleasurable as chewing on a candlestick (steric acid is used as a stiffener in paraffin candles). One thing I remember seeing too is that inflammation increases damage caused by de novo lipogenesis. I am wondering if consumption of stable saturated fats vs. consumption of unstable (and commonly rancid polyunsaturated fats) exasperates things.