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The way I think about it - the higher your fat content in your diet the likely the higher amount of fat (cholesterol) circulating in your blood veins. It might

The way I think about it - the higher your fat content in your diet the likely the higher amount of fat (cholesterol) circulating in your blood veins. It might not be a big deal if your body doesn't attach that fat the walls of your arteries however if you have inflammation in your arteries the fat will attach to the arteries and over time that causes a whole host of problems. My unqualified suspicion is that if you manage inflammation you likely won't arterial walls lined with cholesterol (which is trying to repair the damage to your arterial walls from inflammation). However I also suspect that as you get older your vein structures change and theres probably a time in your 30s-50s where you biology changes and you start adsorbing more cholesterol (from fat) onto your arteries that cause CVD.

oifjsidjf 4y ago
Fat doesn't "attach" to the artery walls. Atherosclerosis is found ONLY in largest arteries where the blood pressure is highest and where the blood vessel splits into 2 because there the fluid (blood) flow gets distorted and slight vortexes are created. Those vortexes then cause the blood pressure to be exerted perpendiculary to the blood vessel wall at artery junctions. It's the high blood pressure + vortices + damaged blood vessel lining that PUSHES particles into the blood vessel walls. There is no atherosclerosis in veins (because those carry blood back to the heart at lower pressure). If fats would "attach" to the blood vessels you'd expect atherosclerosis even in veins, but you never get it there. Also: atherosclerotic plaque is only 0.5% cholesterol and 0.5% fat. The other 99% is "scar tissue" and other stuff. It's time to put this silly "fat attaches to blood vessel walls" thing to rest, it's 2022. You might wish to check out Bart Kay's youtube channel, he explains it nicely there.
- swayvil 4y ago
  What causes the scar tissue? Smoking? Irregular exercise?
  - oifjsidjf 4y ago
    Macrophages/white blood cells who wish to save you from those stuck particles. The real question is what causes the blood vessel walls to get damaged (since the scar tissue is the healing response of the body, but if the damage keeps on piling it grows too much instead of being gradually reduced over time). The problem is that there are millions of causes of inflamation etc... In general the best answer is "modern diet" full of sugars + fat at the same time. Carbs in high doses are poisonus, there is a reason the the lives of diabetics end in limb amputation, blindness and severe pain due to nerve damage due to sugar destroying them from the inside out...
- boringg 4y ago
  Ok so what you are saying is that the particles are pushed into the arterial walls which builds plaque. At some point some of that plaque breaks off and causes a blockage --> heart attack / TIA / Stroke. Agree biggest concern is what is causing damage to the arterial walls. To be fair --> fat + cholesterol attach to the wall in order to repair the arterial wall so, fat does attach to the wall. I'm guessing the scar tissue cell matter attaches to the cholesterol+fat which is trying to repair the wall.
deleted 4y ago
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oifjsidjf 4y ago

Fat doesn't "attach" to the artery walls. Atherosclerosis is found ONLY in largest arteries where the blood pressure is highest and where the blood vessel splits into 2 because there the fluid (blood) flow gets distorted and slight vortexes are created. Those vortexes then cause the blood pressure to be exerted perpendiculary to the blood vessel wall at artery junctions. It's the high blood pressure + vortices + damaged blood vessel lining that PUSHES particles into the blood vessel walls. There is no atherosclerosis in veins (because those carry blood back to the heart at lower pressure). If fats would "attach" to the blood vessels you'd expect atherosclerosis even in veins, but you never get it there. Also: atherosclerotic plaque is only 0.5% cholesterol and 0.5% fat. The other 99% is "scar tissue" and other stuff. It's time to put this silly "fat attaches to blood vessel walls" thing to rest, it's 2022. You might wish to check out Bart Kay's youtube channel, he explains it nicely there.

swayvil 4y ago
What causes the scar tissue? Smoking? Irregular exercise?
- oifjsidjf 4y ago
  Macrophages/white blood cells who wish to save you from those stuck particles. The real question is what causes the blood vessel walls to get damaged (since the scar tissue is the healing response of the body, but if the damage keeps on piling it grows too much instead of being gradually reduced over time). The problem is that there are millions of causes of inflamation etc... In general the best answer is "modern diet" full of sugars + fat at the same time. Carbs in high doses are poisonus, there is a reason the the lives of diabetics end in limb amputation, blindness and severe pain due to nerve damage due to sugar destroying them from the inside out...
boringg 4y ago
Ok so what you are saying is that the particles are pushed into the arterial walls which builds plaque. At some point some of that plaque breaks off and causes a blockage --> heart attack / TIA / Stroke. Agree biggest concern is what is causing damage to the arterial walls. To be fair --> fat + cholesterol attach to the wall in order to repair the arterial wall so, fat does attach to the wall. I'm guessing the scar tissue cell matter attaches to the cholesterol+fat which is trying to repair the wall.

deleted 4y ago

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