Netherlands has ~200-250ish cycling deaths a year with a ~30% modeshare. Half are elderly. About a third are on ebikes 87% involve a car. That's around 0.8

Netherlands has ~200-250ish cycling deaths a year with a ~30% modeshare. Half are elderly. About a third are on ebikes 87% involve a car. That's around 0.8 deaths per hundred thousand people worth of bike modeshare not invovling a car. 1/15th of the USA and a quarter of netherlands road deaths. This is with drunk cycling penalties being almost completely unenforced (although not sure how it compares to US drunk driving prevalence). Granted cars are used for the longer trips so it's not completely sound, but bikes are used for congested trips. Small vehicle modeshare also shortens all trips. My guess is the safest vehicle would look like a train followed by lightweight velo no heavier than a dutch bike (and not optimized for aero) or a recumbent trike with a roll cage and a lap belt. Also we can conclude that either current ebikes are too fast and heavy, or they result in people cycling who would be too frail otherwise.