Svelte / Sveltkit is easy to learn, efficient and separates HTML, JS, CSS nicely (no need to mess around with JSX). It supports Typescript and you get animation

Svelte / Sveltkit is easy to learn, efficient and separates HTML, JS, CSS nicely (no need to mess around with JSX). It supports Typescript and you get animations, global state etc. out of the box. Downside: it's top notch and thus hasn't the biggest ecosystem yet. You can also try Flutter for developing mobile, desktop and web apps. It's got Google's backing and is also supported by Canonical for Ubuntu desktop apps.