4 ms·
20+ year old DNA samples, even stored deeply frozen, could accumulate damage that would be amplified during library prep prior to sequencing. To make the case,
by possiblydrunk 4y ago
20+ year old DNA samples, even stored deeply frozen, could accumulate damage that would be amplified during library prep prior to sequencing. To make the case, they would really need appropriate control samples from the same time periods stored under the same conditions.
- themanmaran 4y agoIt's also worth noting that the samples they used were from a totally different age bracket than the astronauts. Astronauts (aged 37–67) compared to "seven young, healthy individuals."