Awesome tale of your adventure, and well-told. > Her eyes were bright blue like the Fremen in Dune. Fremen eyes were entirely blue. Even their sclera, the "wh

Awesome tale of your adventure, and well-told. > Her eyes were bright blue like the Fremen in Dune. Fremen eyes were entirely blue. Even their sclera, the "whites" of their eyes, were blue. While it is still possible your Bedouin guide had blue sclera, it is vanishingly unlikely to impossible that this was due to melange addiction. But there are plenty of reasons why someone can have blue sclera. Anything that causes a thinning of the sclera could cause it. Some medications, like steroids, can produce blue sclera. Aging and anemia will also give a blue tint to the whites of the eye. While it is usually benign, there are a number of rare but serious disorders that can cause blue sclera, such as Marfan Syndrom, Russell Silver Syndrome, Hallermann-Schermann-Streiff Syndrome, Ehlers-Danlos Syndrome, and others. Thus, if the cause is unknown, anyone with blue sclera should see an ophthalmologist.