2 ms·
New, Non-Addictive Pain Killer with Fewer Side Effects
- socky 4y ago>an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression” benzyloxy-cyclopentyladenosine (BnOCPA) >is an A1R selective agonist discovered to be a "potent and powerful analgesic, but does not cause sedation, bradycardia, hypotension or respiratory depression" https://en.m.wikipedia.org/wiki/Adenosine_A1_receptor https://en.m.wikipedia.org/wiki/Adenosine_A1_receptor Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression https://www.nature.com/articles/s41467-022-31652-2 https://www.nature.com/articles/s41467-022-31652-2