Depends. For a small company the interviewer might well be the beneficiary of your work and in the end he needs you more than you need him. So a good one won't

Depends. For a small company the interviewer might well be the beneficiary of your work and in the end he needs you more than you need him. So a good one won't let his bad day ruin a nice candidate. Also, depends on culture. There are countries where 1:1 interviews with a different gender candidate are okay.