Almost all RCTs involving depression throw a bunch of people diagnosed with "depression", but suffering a variety of conditions, all given that label, in a tank

Almost all RCTs involving depression throw a bunch of people diagnosed with "depression", but suffering a variety of conditions, all given that label, in a tank together. The treatment may help a few, harm others, and have no effect on the rest, and the treatment is then labeled "ineffective". RCTs depend for validity absolutely upon precise, accurate diagnosis for validity. Bad diagnostics => meaningless results. RCTs are not magic. They can be as wrong as anything stupidly performed. RCTs around depression are worse than most.