5 ms·
Do you know if supratherapeutic dose of B6 combined with a megadose of B1 would avoid peripheral neuropathy? Already people taking DCA (peripheral neuropathy-in
by bitL 4y ago
Do you know if supratherapeutic dose of B6 combined with a megadose of B1 would avoid peripheral neuropathy? Already people taking DCA (peripheral neuropathy-inducing as well) take megadoses of B1 to avoid that issue.
- hereme888 4y agoThey're talking about B6. It's not worth risking permanent nerve damage until further studies clarify things.
- bitL 4y agoI meant B6, not sure why I made the B2 typo. Fixed.
- bastawhiz 4y agoWhat clinical evidence is there that the neuropathy would be avoided? Feels very "old lady who swallowed a fly" to mitigate the risks of supertherapeutic doses of one compound with megadoses of another compound. Why would you tolerate that risk?
- bitL 4y agoB1 seems to be safe at any levels (excess excreted in urine and helps kidneys in addition) and is popular among people with peripheral neuropathy.
- bastawhiz 4y agoPeripheral neuropathy is the symptom, not the underlying issue. Zyrtec is popular among people who frequently sneeze but it's probably not what you're looking for if you're ingesting so much of a substance that it makes you sneeze uncontrollably. Do you really want to be the person who has to explain to the doctor that you have no feeling in your hands because you're taking so much B6 every day for a bit of anxiety relief that it fried your nerves, but you thought that you could just cancel it out by taking a ridiculous amount of B1? Especially when there's so much else that can treat anxiety, including well-studied and benign things like lavender oil?