4 ms·
Cell death: you're fired, pack your stuff, it's too risky for you to stay Cell senescence: stay, but your contract won't be renewed I wonder if it's possible
by adrianwaj 15y ago
Cell death: you're fired, pack your stuff, it's too risky for you to stay
Cell senescence: stay, but your contract won't be renewed
I wonder if it's possible to reactivate a senescent cell by repairing the damage that triggered it in the first place: repair and rejuvenation.
Add: possibly no: "repair to DNA normally take place during DNA replication when cells are dividing, but post-mitotic cells do not divide. The main concern in this instance is not whether there is a decrease in the ability of cells to repair DNA with age, but instead whether post-mitotic cells can themselves repair DNA, if at all they need to"
http://ageing-research.blogspot.com/2008/01/post-mitotic-tissue_21.html http://ageing-research.blogspot.com/2008/01/post-mitotic-tis...
Also, is it possible to replace a cell that has already suicided by causing an improvement in conditions that'd ensure a replacement cell isn't tagged with the same fate: reconditioning and recruitment.