Can I recommend an additional intervention to look into? https://en.m.wikipedia.org/wiki/Diosmin https://en.m.wikipedia.org/wiki/Diosmin — a chemical relative

Can I recommend an additional intervention to look into? https://en.m.wikipedia.org/wiki/Diosmin https://en.m.wikipedia.org/wiki/Diosmin — a chemical relative of hesperidin (a blood thinner like curcumin), but not itself a blood thinner — rather, diosmin affects lymphatic channel contractile tone in about the same way that hesperidin affects blood-vessel contractile tone. I.e. it makes your body better at pumping lymph. Currently used by many for treatment of chronic veinous insufficiency (“spider veins”), as a side-effect of improved lymph flow is lower peripheral static pressure in cases of low veinous return rate. Also treats peripheral oedema, for similar reason. But that’s just a side-effect. More interesting direct effect: it expedited wound healing (waste clearance from wound site), and decreases wound scarring. I.e. it makes your body do the thing it relies on your lymphatic system to do, faster and better. (Tattoos fade faster, even.) Consequently, diosmin is the active ingredient of a an oral OTC anti-hemorrhoid drug. Because, by improving wound healing + lowering scarring enough, your body can clear wastes/senescent cells/etc faster than they can form into a hemorrhoid. Obviously, a compound that can do this could be potentially of use in modulating all sorts of other inflammatory processes — but it’s critically under-researched, especially in chronic inflammation.