I cannot imagine sitting in one place when working. I move, with my laptop, from desk to the couch to the outside table to the gym to the coffee shop to the bar

I cannot imagine sitting in one place when working. I move, with my laptop, from desk to the couch to the outside table to the gym to the coffee shop to the bar. If I had a desktop, it would gather dust in 2 seconds flat. But then you did say ignoring portability, so it depends what you value most, as most things do.