> the risk of developing lung adenocarcinoma was increased, possibly by weakening of the tumorigenesis-barrier effect of cell senescence - The proposed mechan

> the risk of developing lung adenocarcinoma was increased, possibly by weakening of the tumorigenesis-barrier effect of cell senescence - The proposed mechanism of why there is an increase in lung adenocarcinoma makes sense to me: Because of NAC and its antioxidant effects, cells were living longer in these mice; much longer than usual. While predictably, this caused lower rates of lung emphysema, it had an adverse effect of increased cancer risk due to messing with harmony of cell cycle arrest (cellular senescence).