This paper is looking at both inherited genes, that is genes that you get from your parents, and de-novo mutations, that is a mutation that only the offspring h

This paper is looking at both inherited genes, that is genes that you get from your parents, and de-novo mutations, that is a mutation that only the offspring has, that wasn't directly copied from a parent. We've known for a while that autism is highly heritable. This paper builds on a large body of work that links specific genes to autism's heritability. I haven't dug into the specific breakdown, but my understanding is that a majority of genetic variants associated with autism are inherited, rather than the random de-novo (new) mutations.