LD50 only tells you acute lethal toxicity. LD50 can be astronomically high and a compound might still have long term, non-lethal toxic effects like injuring spe

LD50 only tells you acute lethal toxicity. LD50 can be astronomically high and a compound might still have long term, non-lethal toxic effects like injuring specific tissues. No one is even suggesting lethal toxicity is the issue here, so how is it relevant?