Is LD50 a meaningful measurement for biopersistent and accumulated compounds? It seems like it would be quite useless, or worse, misleading. I recall that larg

Is LD50 a meaningful measurement for biopersistent and accumulated compounds? It seems like it would be quite useless, or worse, misleading. I recall that large blobs of mercury was used as a homemade remedy for stomach issues which turned out to not be a great idea for obvious reasons, although it's LD50 would probably have been similarly high.