Not saying it's impossible, but I've never heard of it happening in that direction[0]. The immune system uses natural selection to randomly generate and amplif

Not saying it's impossible, but I've never heard of it happening in that direction[0]. The immune system uses natural selection to randomly generate and amplify successful antibodies. It seems that the likelihood of generating exactly that antibody in the immunization process is astronomically low. [0] unless the lab-gnerated antibody is "seeing" a different part of the virus that the current vaccine doesn't see, in which case targeting the new spot in the virus is an obvious "next move".