3 ms·
> TL;DR: new antibiotic candidate effective against gram-negative bacterias, which are generally resistant against most antibiotics because of their thick cell
by csdvrx 4y ago
> TL;DR: new antibiotic candidate effective against gram-negative bacterias, which are generally resistant against most antibiotics because of their thick cell walls and efflux pumps
Aren't mycins something very well known and not novel at all?
I see them listed in https://en.wikipedia.org/wiki/List_of_antibiotics https://en.wikipedia.org/wiki/List_of_antibiotics along with a link to https://en.wikipedia.org/wiki/Aminoglycoside https://en.wikipedia.org/wiki/Aminoglycoside that explain they work against gram-negative bacterias
- flobosg 4y ago“Mycin” is a suffix used in antibiotics, but does not represent a specific category anymore. If you look at the structure of fabimycin you will see that it does not resemble an aminoglycoside at all.
- John23832 4y agoThere are many bacteria that are developing resistance (or are totally resistant) to some mycins (macrolides, particularly azithromycin). Gonorrhea being a HUGE one.