Many if not most countries have preferred front-line treatments, usually decided by a combination of overall costs. These costs will include things like actual

Many if not most countries have preferred front-line treatments, usually decided by a combination of overall costs. These costs will include things like actual monetary cost, how closely you need to be monitored by your doctors (blood tests and stuff), how severe side effects are, how much the reduce disability in the long term, the ability of patients to stick with it and things like that.