3 ms·
I think the more important factor here is internal body temperature, and if people living in colder climates exhibit the sorts of adaptations related in the art
by TrevorJ 4y ago
I think the more important factor here is internal body temperature, and if people living in colder climates exhibit the sorts of adaptations related in the article. It's quite possible to be outdoors in very cold conditions and have little to no core body temperature changes.
- srvmshr 4y agoAFAICT, homeostatic temperature in humans does not vary by a great deal. It is 37±1°C always. I haven't come across a study where any large deviation was stated. Human bodies lose heat very quickly. We evolved from a primate line which lived in South Central African plains. Our hand/feet digits are great radiators. Although still debated, our skin tone originally could have been light, much like the skin under the primate coats (with brown and African skin tones being later developments in evolution, when we started to get less furry & produced higher melatonin). So the evidence generally points in the direction that we are just another warm-blooded species without much thermal attributes. Given that, environment should show some kind of statistical difference if this cancer pathway's reliance on temperature is so pronounced. Its hard to measure, because there are several confounders in the biochemistry. It is also hard to find a body of people who have lived in both cold & hotter climates simultaneously to make direct comparisons Edit: some more details.
- runamok 4y agoI think you mean melanin vs. melatonin. https://en.m.wikipedia.org/wiki/Melanin https://en.m.wikipedia.org/wiki/Melanin