I've had good success with the lutris launcher. For certain problematic apps/games (GTA5 for example), it has the option to use its own heavily patched wine tha

I've had good success with the lutris launcher. For certain problematic apps/games (GTA5 for example), it has the option to use its own heavily patched wine that fixes tons of programs and makes them usable and often more performant, including options to use DXVK (Vulkan translation layer for later DirectX versions) or dgVoodoo2 (software emulation of old DirectX/Glide versions). Every app also gets its own wine prefix and you can still choose to use the stock wine for some apps if desired. Best thing is that it doesn't rely on proton or steam/valve in any way and respects your privacy.