3 ms·
Why does this tired argument always appear on HN? We share 97% of our genes with mice. Our organ systems and metabolic pathways are extremely similar. Our home
by caeril 4y ago
Why does this tired argument always appear on HN?
We share 97% of our genes with mice. Our organ systems and metabolic pathways are extremely similar. Our homeostatic mechanisms are nearly identical.
Some mouse models don't carry over to us, to be sure. But the reality is that most do. Do we know for a fact that this paper applies to us? No. But it significantly updates our priors. And that's always noteworthy.
- d0mine 4y ago9 out 10 results in mice do not transfer to humans. For example, fasting for several hours in mice and in humans are completely different things (a human would have to fast for days to get similar results).