4 ms·
> The reported acute effects were significantly more intense for the active dose compared to the placebo, but only for participants who correctly identified the
by superb-owl 4y ago
> The reported acute effects were significantly more intense for the active dose compared to the placebo, but only for participants who correctly identified their experimental condition
I find attempts to study psychedelics with placebo control kind of comical. The positive effects are not due to a chemical change, they are due to a direct subjective experience [1][2]. It's like trying to placebo control the effects of reading a good novel or seeing a sunset.
But I guess this does help to dispel the similarly comical idea that a completely non-psychoactive dose of psychedelics can be beneficial.
[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033615/#:~:text=Finally%2C%20in%20a%20psilocybin%20study,again%20suggesting%20some%20specificity%20to https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033615/#:~:tex...
[2] https://superbowl.substack.com/i/65186479/the-psychedelic-experience https://superbowl.substack.com/i/65186479/the-psychedelic-ex...
- mlindner 4y ago"Experience" is a thing represented by chemical markers in the brain however. It's all electrochemical in the end. And I have heard first hand stories directly from people who used to use the stuff that it absolutely changed their personalities, i.e. brain damage which is a chemical effect.