4 ms·
About TMAO: this is produced when intestinal bacteria consume choline. They release trimethylamine as a byproduct, which is then oxidized in the liver to TMAO.
by Metacelsus 4y ago
About TMAO: this is produced when intestinal bacteria consume choline. They release trimethylamine as a byproduct, which is then oxidized in the liver to TMAO. If the liver enzymes are mutated you wind up with "fish malodor syndrome" due to smelling like trimethylamine.
Anyway, any food high in choline will elevate TMAO.
As an undergrad I was briefly involved in an effort to develop an inhibitor of the bacterial enzymes that degrade choline.