4 ms·
> The whole transformative experience is the "trip" itself. IMHE, it's not, at least in regards to (racemic) ketamine and depression. The benefit doesn't appea
by WalterSear 4y ago
> The whole transformative experience is the "trip" itself.
IMHE, it's not, at least in regards to (racemic) ketamine and depression. The benefit doesn't appear until ~24 hours later, and the effect scales with dosage, but not trip intensity or outcome.
I found taking it almost unpleasant at times, but the subsequent effects uniformly profound. Unfortunately, I developed a rare health issue, or I'd still be taking it.
- debenedictis 4y agoI too developed a rare health issue, OABSS. "In our study, OABSS (overactive bladder symptom score) significantly increased with the combined use of ketamine and marijuana (P = 0.016). Cannabinoids are the active components of marijuana, and select cannabinoid receptors, CB1 and CB2, have been identified in the human detrusor and urothelium." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510790/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510790/