6 ms·
It’s amazing watching them wash away/make irrelevant decades of academic effort
by greatpostman 4y ago
It’s amazing watching them wash away/make irrelevant decades of academic effort
- tragictrash 4y agoCould you elaborate on this? I have no idea what you're talking about.
- izzydata 4y agoIf I had to take a guess I'd say that in the past it took a ton of work to record and catalog just a small number of these and now they can brute force find and record them so quickly that it makes the past efforts look like a waste of time. Although I suspect that this new thing wouldn't have been possible without the old thing.
- photochemsyn 4y agoThis is really more of a tool that allows researchers to take protein sequences and get pretty good predictions of what the crystallized protein will look like. It might be an aid to crystallization as well as you can look at crystallization conditions of similar proteins. However, claims that real-world data is no longer needed are certainly overblown. Another issue is that a complete analysis of a protein's function, particularly catalytic proteins, requuires that you understand their dynamics, which are not reflected in static protein crystals. Other methods like NMR are used for that purpose.