Part of why the best tools take so long is that they are trying really hard, but an amateur approach can do a decent job in far less time by trying less hard. (

Part of why the best tools take so long is that they are trying really hard, but an amateur approach can do a decent job in far less time by trying less hard. (No fuzzy matching, only exact matching on shortish chunks) Additionally, we're talking about nanopore data, which is much longer reads, and so is going to be computationally a bit easier.