High molecular weight assemblies of Abeta have been repeatedly identified by numerous researchers from human tissue and other sources. However, similar to myse

High molecular weight assemblies of Abeta have been repeatedly identified by numerous researchers from human tissue and other sources. However, similar to myself, Derek Lowe didn't investigate the voluminous literature on the topic to see if the specific Aβ*56 species has been found in extracts of human tissue by others. With a little extra searching, I found this article below which does appear to replicate detection of a potential 56 kDa form of Aβ in human tissue by western blot of SDS-PAGE gels, as shown in the Lesné paper (Figure 1), though they express concern that its true concentrations may be very low and may be artefacts. https://onlinelibrary.wiley.com/doi/full/10.1111/j.1582-4934.2011.01306.x https://onlinelibrary.wiley.com/doi/full/10.1111/j.1582-4934...