It's not even the toxic oligomer hypothesis that is undermined - it is only the role of amyloid beta as a primary driver of Alzheimer's pathology. This isn't ev

It's not even the toxic oligomer hypothesis that is undermined - it is only the role of amyloid beta as a primary driver of Alzheimer's pathology. This isn't even out of nowhere, there's been plenty of data finding no strong association between AB levels and pathology. Most data seems to point to AB being more of a supporting element, with tau amyloids actually being associated with toxicity and resultant functional deficits.