3 ms·
The linked article is sensationalized an disingenuously mixes the author's opinion with straight reporting on the Science article[0] previously discussed here[1
by onionisafruit 4y ago
The linked article is sensationalized an disingenuously mixes the author's opinion with straight reporting on the Science article[0] previously discussed here[1]. Science never suggests that anybody other than Lesné was involved in falsifying results, and even then it is careful to not accuse him of deliberate fraud. Neither article suggests who the second scientist referenced in the headline may be.
I suspect there was deliberate fraud, but this article doesn't provide any more evidence of that than previous articles.
> Since that 2006 publication, the presence or absence of this specific amyloid has often been treated as diagnostic of Alzheimer’s. Meaning that patients who did die from Alzheimer’s may have been misdiagnosed as having something else. Those whose dementia came from other causes may have falsely been dragged under the Alzheimer’s umbrella.
I think the author is confused about the controversy he is reporting on. Nobody is suggesting that there aren't elevated levels of Aβ in Alzheimer's brains. The controversy is only about the presence of Aβ56, and as far as I know Aβ56 was never used to diagnose Alzheimer's disease. It should also be noted that this is only relevant to postmortem diagnosis, so even if they were testing for Aβ*56 it wouldn't have affected the diagnosis of living patients.
At the bottom of the article is a note, "Article written by Mark Sumner via Daily Kos". This explains a lot. Daily Kos is a site that got its start with sensationalized political articles. Now they've apparently expanded to subjects where they can do more damage.
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As I post the comment, the title of the linked article is: "Two decades of Alzheimer’s research was based on deliberate fraud by 2 scientists that has cost billions of dollars and millions of lives"
[0] https://www.science.org/content/article/potential-fabrication-research-images-threatens-key-theory-alzheimers-disease https://www.science.org/content/article/potential-fabricatio...
[1] https://news.ycombinator.com/item?id=32183302 https://news.ycombinator.com/item?id=32183302