It may be safe in by itself, but using a painkiller only masks the pain, the underlying issue is addressed later or never and that can create problems for you.

It may be safe in by itself, but using a painkiller only masks the pain, the underlying issue is addressed later or never and that can create problems for you. Also when the body signals with pain, that needs attention and treatment, taking painkillers frequently may make one ignore a real problem, which perhaps had it been taken more seriously and treated earlier may save lives.