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Yeah, I’m vaxxed. The point I’m trying to make is that there’s a wide range of vaccine efficacy. Current vaccines against BA4/5, very poor. Now, my question i
by wrycoder 4y ago
Yeah, I’m vaxxed.
The point I’m trying to make is that there’s a wide range of vaccine efficacy. Current vaccines against BA4/5, very poor.
Now, my question is, since the current mRNA vaccine is causing our body to create old spike protein, and BA4/5 almost completely evades the resulting antibodies, what’s the mechanism that reduces severe disease from BA4/5?
- jhugo 4y ago> since the current mRNA vaccine is causing our body to create old spike protein Your body only briefly produced spike protein after vaccination. The lasting immunity isn't caused by ongoing spike protein production.
- wrycoder 4y agoWhat is it caused by? It’s not like T cell immunity has whole SARS2 virus to model against, like it does with other vaccines employing whole, inactivated virus.
- jhugo 4y agoThere isn't really a meaningful difference; either way the immune system is responding to a protein and "remembering" it. mRNA breaks down within a few days, by which point spike protein production by your cells has stopped, and the spike proteins themselves break down within a few weeks. Inactivated virus would be broken down and excreted within a similar timeframe or faster; it's the immune system memory of the proteins that it encountered that persists.