People who change their gender, or exhibit traits of the opposite gender, aren’t relevant to this conversation. Well, they can be – treatment with e.g. hormone

People who change their gender, or exhibit traits of the opposite gender, aren’t relevant to this conversation. Well, they can be – treatment with e.g. hormone therapy has obvious physiological impacts with subsequent influence on the effect of other medical treatments. Nobody serious doubts that there exist sex-linked physiological characteristics; in reality, the original statement that "sexual dimorphism is real" isn't intended to share knowledge, but a subtle signal about something else.