I had the same feedback talking to a few professionals. There is doubt about the exact effect of the prescription and the science behind it, and they regularly

I had the same feedback talking to a few professionals. There is doubt about the exact effect of the prescription and the science behind it, and they regularly have patients that get no clear effect from commonly prescribed treatments. But they also see other patients showing measurable improvement, and trying different prescriptions until finding one that seem to have an effect is a common practice. All in all, this is very murky situation, but drug prescription can still be effective and might be the only option for some patient for who other approaches didn't work.