4 ms·
Do you have links to more info on this? Sort of an armchair pharmocologist and had never heard this about gabapentin. I thought it was a straight up gaba agonis
by DontchaKnowit 4y ago
Do you have links to more info on this? Sort of an armchair pharmocologist and had never heard this about gabapentin. I thought it was a straight up gaba agonist like phenibut. But makes sense that it would be different given its very unusual dose response curve/self potentiation.
(Probably making anyone who actually knows what they're talking about cringe. Take it easy, lol)
- refurb 4y agoGabapentin was designed as an antagonist (the structure is basically GABA with a big bulky group on it). You can just google older papers on gabapentin. Just like most drugs it impacts a number of different receptors in the body. We still don't fully understand them all.