3 ms·
> [...] due to proximal oxidative and inflammatory effects upon them. No, this is not true.
by tpush 4y ago
> [...] due to proximal oxidative and inflammatory effects upon them.
No, this is not true.
- orangepurple 4y agoIt absolutely is true for many reasons; one of them is uptake of ox-LDL by macrophage and their conversion into foam cells. More info: https://www.ncbi.nlm.nih.gov/books/NBK326741/ https://www.ncbi.nlm.nih.gov/books/NBK326741/ Additionally, ApoB is an excellent biomarker of cardiovascular health risk.
- tpush 4y agoI agree with ApoB being the marker for CVD risk. What I'm disagreeing with is the statement that pathogenesis is caused by inflammation and/or oxidization; instead I'd say it's the number of particles that's the primary cause, with the rest of the mechanism following. Might just be semantic quibbling, though.