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To expand upon this, Cholesterol is wrapped in lipoprotein, and pathogenesis is caused by malfunction of lipoproteins due to proximal oxidative and inflammatory
by orangepurple 4y ago
To expand upon this, Cholesterol is wrapped in lipoprotein, and pathogenesis is caused by malfunction of lipoproteins due to proximal oxidative and inflammatory effects upon them.
- kelp 4y agoSo what’s the cause of high cholesterol and how do you lower it?
- zackees 4y ago
- theNJR 4y agoBuckle up https://peterattiamd.com/why-there-is-no-bad-or-good-cholesterol/ https://peterattiamd.com/why-there-is-no-bad-or-good-cholest...
- justin66 4y agohttps://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/symptoms-causes/syc-20350800 https://www.mayoclinic.org/diseases-conditions/high-blood-ch...
- tpush 4y ago> [...] due to proximal oxidative and inflammatory effects upon them. No, this is not true.
- orangepurple 4y agoIt absolutely is true for many reasons; one of them is uptake of ox-LDL by macrophage and their conversion into foam cells. More info: https://www.ncbi.nlm.nih.gov/books/NBK326741/ https://www.ncbi.nlm.nih.gov/books/NBK326741/ Additionally, ApoB is an excellent biomarker of cardiovascular health risk.
- tpush 4y agoI agree with ApoB being the marker for CVD risk. What I'm disagreeing with is the statement that pathogenesis is caused by inflammation and/or oxidization; instead I'd say it's the number of particles that's the primary cause, with the rest of the mechanism following. Might just be semantic quibbling, though.