It cannot do CNAME uncloaking because Chrome's extension API do not provide dns resolving like on Firefox. Another example if HTML filtering where on Firefox an

It cannot do CNAME uncloaking because Chrome's extension API do not provide dns resolving like on Firefox. Another example if HTML filtering where on Firefox an extension can rewrite the HTML from requests on the fly (e.g. to remove script tags, etc.). That's also not possible on Chrome and uBlock Origin will only make use of this on Firefox. There are probably more limitations, these are just two from the top of my head.