I have a local NAS (running TrueNAS) and use Time Machine on it for recovery style backups, any important media, documents, etc are synced separately via Syncth

I have a local NAS (running TrueNAS) and use Time Machine on it for recovery style backups, any important media, documents, etc are synced separately via Syncthing to a separate volume in TrueNAS that is synced to Backblaze on a schedule. Bonus is that Syncthing is really good for syncing development working directories between machines when you don't want to use Git because unlike dropbox it lets you exclude things like node_modudules.