3 ms·

I've experienced an allergic reaction to medication before. It was the worst hour of my entire life until I had an injection of Benadryl. Every moment, I felt l

• mlyle 4y ago
  > So sure, experimentation effects may vary but the upper limit is fucking brutal and definitely depends on what stage the drug is in. Early on in development, the effects could be worse than death. So could the effects of e.g. life in the wild. Anything can go very badly. IMO: You can't be completely blind to the utilitarian angle. The average and distribution of outcomes matters. So, we go through an escalating series of tests-- designed to both weed-out drugs cheaply and to avoid suffering; from conceptual models to computation to tissue cultures to organ models to small animals to larger animals to small numbers of humans to large numbers of humans. If you weed out the last couple of steps before humans, you're going to either try a lot fewer drugs on humans, or increase human suffering a whole lot to protect smaller animals.
  • goldenkey 4y ago
    That sounds fair to me. If we want to get the benefit of something, we ought to pay the price. Not offload it to some poor soul, literally.