3 ms·
Incidentally my sister just got a paper published in the New England Journal with a similar approach (kill switch) for use in gene therapy http://www.nejm.org/d
by teyc 15y ago
Incidentally my sister just got a paper published in the New England Journal with a similar approach (kill switch) for use in gene therapy http://www.nejm.org/doi/full/10.1056/NEJMoa1106152 http://www.nejm.org/doi/full/10.1056/NEJMoa1106152
This could be pretty important work to make gene therapy much safer.
A single dose of dimerizing drug, given
to four patients in whom GVHD developed,
eliminated more than 90% of the modified
T cells within 30 minutes after
administration and ended the GVHD
without recurrence.