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Note that this tech is similar to what's used by Novavax (and that HPV vaccine Gardasil); both use virus-like nanoparticles. The main innovation here appears t

Note that this tech is similar to what's used by Novavax (and that HPV vaccine Gardasil); both use virus-like nanoparticles. The main innovation here appears to be the use of a variety of spike proteins instead of just one.

Traubenfuchs 4y ago
As usual when the HPV vaccine is mentioned, I want to stress how important it is to get it, for anyone but those that absolutely do not have sex. HPV can cause warts and serious cancers in the mouth/throat, anus, penis and vaginal tract/cervix. Warts alone can be a severe mental and physical burden requiring several visits to a dermatologist and potentially extremely dangerous medicine like Imiquimod. The HPV vaccines protect against the most dangerous of the many known HPV strains. The HPV vaccines are even assumed to be a therapy for infection already present. Many people have at least a few HPV strains somewhere in their body. Almost everyone who engages in casual sex has them. HPV has been promoted primarily for women, to protect against cervical cancer, but men are also at risk: It can cause cancer at/in your penis, anus and throat! MSM (men having sex with men) are especially at risk.
- Trouble_007 4y ago
  FYI; Human Papilloma Virus (HPV) Vaccines : https://en.m.wikipedia.org/wiki/HPV_vaccine https://en.m.wikipedia.org/wiki/HPV_vaccine
- bigDinosaur 4y ago
  Public health messaging has been excruciatingly slow here too, it's gradually being recommended more and more for males too in the last few years by public health agencies as an actual health intervention for males (previously the idea was more about reducing transmission to females). So yes, second this, everyone should get this vaccine, and it's probably not too late to get some benefit from it since there are multiple strains you can vaccinate against (you'll almost certainly have some strains if you're aged 20+ though). That said, for multiple reasons there's no real need to panic and rush out to get it if you're older and monogamous.
  - Traubenfuchs 4y ago
    I paid about 450€ for the 3x HPV vaccine series in Austria, which is absurd. In my time as casual sex addict I have seen three cases of severe anal condylomata outbreaks that I all sent to a dermatologist, all three not vaccinated. I myself had two anal warts (interestingly, right after the second vaccine) that I got cut out, luckily they never came back.
    - config_yml 4y ago
      After looking at your profile I'm left wondering if this is a made up story by GPT-3 or if this is actually the creator of the account commenting.
      - Traubenfuchs 4y ago
        The uncertainty caused in most people that engage after having read the claim is the highest honor. Knowing the truth wouldn't change the interaction. It wouldn't change me. It would only change something inside of your head. Thus, does it matter?
        bigDinosaur 4y ago
        This is pretty GPT-3'ish. Yes, it matters.
        Traubenfuchs 4y ago
        Then we agree to disagree. I will end the discussion at this point. Q.E.D.
      - bigDinosaur 4y ago
        If GPT-3 is that good then in this case it's still offering good public health advice. I think it's a person posting but with the GPT-3 thing as their description as that'd be pretty funny, but unless there are obvious errors we'll never know.
- everdrive 4y ago
  Is the HPV useful for someone who already has HPV, but is asymptomatic, and does not know it?
  - Traubenfuchs 4y ago
    There is some evidence that at least some HPV vaccines can help against existing, symptomatic HPV.* The one I linked was with a quadrivalent HPV vaccine, so, not the Gardasil-9 that is currently in use. I know there are even more case reports about this topic out there. If it works like that for already symptomatic infection, it will work equally or better against asymptomic / presymptomatic infection. But, an authoritative answer to your question does not exist. * https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-020-8371-z https://bmcpublichealth.biomedcentral.com/articles/10.1186/s... Besides that, there is the high likelihood that you aren't infected with all variants of HPV the vaccine protects against, so go for it. I can only repeat my claim, that getting the HPV vaccination series is a good idea for almost everyone at every age (the younger the better), besides almost esoteric exceptions (e.g. those severely immunocompromised people that also don't create covid vaccine antibodies and monks with life long sexual abstinence).

Traubenfuchs 4y ago

As usual when the HPV vaccine is mentioned, I want to stress how important it is to get it, for anyone but those that absolutely do not have sex. HPV can cause warts and serious cancers in the mouth/throat, anus, penis and vaginal tract/cervix. Warts alone can be a severe mental and physical burden requiring several visits to a dermatologist and potentially extremely dangerous medicine like Imiquimod. The HPV vaccines protect against the most dangerous of the many known HPV strains. The HPV vaccines are even assumed to be a therapy for infection already present. Many people have at least a few HPV strains somewhere in their body. Almost everyone who engages in casual sex has them. HPV has been promoted primarily for women, to protect against cervical cancer, but men are also at risk: It can cause cancer at/in your penis, anus and throat! MSM (men having sex with men) are especially at risk.

Trouble_007 4y ago
FYI; Human Papilloma Virus (HPV) Vaccines : https://en.m.wikipedia.org/wiki/HPV_vaccine https://en.m.wikipedia.org/wiki/HPV_vaccine
bigDinosaur 4y ago
Public health messaging has been excruciatingly slow here too, it's gradually being recommended more and more for males too in the last few years by public health agencies as an actual health intervention for males (previously the idea was more about reducing transmission to females). So yes, second this, everyone should get this vaccine, and it's probably not too late to get some benefit from it since there are multiple strains you can vaccinate against (you'll almost certainly have some strains if you're aged 20+ though). That said, for multiple reasons there's no real need to panic and rush out to get it if you're older and monogamous.
- Traubenfuchs 4y ago
  I paid about 450€ for the 3x HPV vaccine series in Austria, which is absurd. In my time as casual sex addict I have seen three cases of severe anal condylomata outbreaks that I all sent to a dermatologist, all three not vaccinated. I myself had two anal warts (interestingly, right after the second vaccine) that I got cut out, luckily they never came back.
  - config_yml 4y ago
    After looking at your profile I'm left wondering if this is a made up story by GPT-3 or if this is actually the creator of the account commenting.
    - Traubenfuchs 4y ago
      The uncertainty caused in most people that engage after having read the claim is the highest honor. Knowing the truth wouldn't change the interaction. It wouldn't change me. It would only change something inside of your head. Thus, does it matter?
      - bigDinosaur 4y ago
        This is pretty GPT-3'ish. Yes, it matters.
        Traubenfuchs 4y ago
        Then we agree to disagree. I will end the discussion at this point. Q.E.D.
    - bigDinosaur 4y ago
      If GPT-3 is that good then in this case it's still offering good public health advice. I think it's a person posting but with the GPT-3 thing as their description as that'd be pretty funny, but unless there are obvious errors we'll never know.
everdrive 4y ago
Is the HPV useful for someone who already has HPV, but is asymptomatic, and does not know it?
- Traubenfuchs 4y ago
  There is some evidence that at least some HPV vaccines can help against existing, symptomatic HPV.* The one I linked was with a quadrivalent HPV vaccine, so, not the Gardasil-9 that is currently in use. I know there are even more case reports about this topic out there. If it works like that for already symptomatic infection, it will work equally or better against asymptomic / presymptomatic infection. But, an authoritative answer to your question does not exist. * https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-020-8371-z https://bmcpublichealth.biomedcentral.com/articles/10.1186/s... Besides that, there is the high likelihood that you aren't infected with all variants of HPV the vaccine protects against, so go for it. I can only repeat my claim, that getting the HPV vaccination series is a good idea for almost everyone at every age (the younger the better), besides almost esoteric exceptions (e.g. those severely immunocompromised people that also don't create covid vaccine antibodies and monks with life long sexual abstinence).