The only commercial CL I've used is Lispworks, which is an awesome product. However, the main reason i bought Lispworks was because of its GUI component (CAPI)

The only commercial CL I've used is Lispworks, which is an awesome product. However, the main reason i bought Lispworks was because of its GUI component (CAPI) which turned out to be crap. I now use CCL when I need a native Cocoa interface, and SBCL when I don't. Clojure vs. Common Lisp? I haven't really given Clojure a fair shot because I don't like the idea of targeting a virtual machine. Common Lisp (at least the implementations I use) generate code for an actual machine.