I would note that the grandparent was not disputing the upcoming 'hardship, difficulty and pain' (i.e. 'doom and negativity') that come with procreation, so at

I would note that the grandparent was not disputing the upcoming 'hardship, difficulty and pain' (i.e. 'doom and negativity') that come with procreation, so at least that bit does not seem to be out of place.