4 ms·

Iron is also needed in the electron transport chain as a component of cytochrome C oxidase. If fewer iron molecules are being prioritized for creating this enz

Iron is also needed in the electron transport chain as a component of cytochrome C oxidase. If fewer iron molecules are being prioritized for creating this enzyme, then less oxygen will be reduced at a time. The rest of the Krebs cycle can be in an optimal state but the cycle can only go as fast as the electron transport chain will allow it. I imagine that given a deficiency, the human body will prioritize iron formation in the blood over creating new cytochrome C oxidase since transporting oxygen to cells is more important than running the Krebs cycle at full speed. I have no idea if this is really what's going on, and it's interesting that this is not mentioned in the linked articles. The reduction of oxygen is really the final step for oxygen before it becomes a part of metabolic water, and throwing off the timing of binding oxygen atoms with protons will slow everything down.

adrian_b 4y ago
Your hypothesis is plausible, but as you have said, whether it is true or not depends on the order in which the availability of iron for each of its many functions in the body becomes affected when iron is scarce. Cytochrome C oxidase needs not only iron, but also copper. So any symptoms caused by an iron deficiency to it, presumably a decrease in the capacity for aerobic effort, should also appear in the case of a copper deficiency.
- phkahler 4y ago
  >> Your hypothesis is plausible, but as you have said, whether it is true or not depends on the order in which the availability of iron for each of its many functions in the body becomes affected when iron is scarce. I just assume that every logical/plausible concept is at play and evolution does its best to balance everything. Rarely is anything absolute.
samstave 4y ago
>>...prioritize iron formation in the blood over creating new _-_-cytochrome-_-_ C oxidase since transporting oxygen to cells is more important than running the Krebs cycle at full speed. https://en.wikipedia.org/wiki/Cytochrome https://en.wikipedia.org/wiki/Cytochrome Whats really interesting to me is the above statement related to a longtime conspiracy-curriosity about the 'Russian kid from Mars' ala an 'Indigo Child' and when back in the ~1990s or some time when he was interviewed, he was ~10 years old and he said that "Humans came from Mars, and after we got to earth, is when we started to age - because Earth is oxigen based, and breathing oxygen is what makes you age." And this crazy piece talks about the iron found in the martian atmosphere: http://www.nuclearplanet.com/Martian%20Iron.html http://www.nuclearplanet.com/Martian%20Iron.html >>The atmosphere of Mars is 95.7% carbon dioxide (CO2), which is available everywhere at the surface and which can readily be compressed. The Martian carbon dioxide can be, simultaneously, a source of carbon monoxide (CO) and a source of oxygen (O2) through the thermal decomposition reaction: >>*2 CO2 → 2 CO + O2 (20.2)* >>Reaction Eq. (20.2) requires a temperature of about 1100C. Note that the iron reduction reaction Eq. (20.1) can take place at about 700C, but a higher temperature, such as 900C, would be desirable. --- What happens if a Nuke goes off in the Martian atmosphere?

adrian_b 4y ago

Your hypothesis is plausible, but as you have said, whether it is true or not depends on the order in which the availability of iron for each of its many functions in the body becomes affected when iron is scarce. Cytochrome C oxidase needs not only iron, but also copper. So any symptoms caused by an iron deficiency to it, presumably a decrease in the capacity for aerobic effort, should also appear in the case of a copper deficiency.

phkahler 4y ago
>> Your hypothesis is plausible, but as you have said, whether it is true or not depends on the order in which the availability of iron for each of its many functions in the body becomes affected when iron is scarce. I just assume that every logical/plausible concept is at play and evolution does its best to balance everything. Rarely is anything absolute.

samstave 4y ago

>>...prioritize iron formation in the blood over creating new _-_-cytochrome-_-_ C oxidase since transporting oxygen to cells is more important than running the Krebs cycle at full speed. https://en.wikipedia.org/wiki/Cytochrome https://en.wikipedia.org/wiki/Cytochrome Whats really interesting to me is the above statement related to a longtime conspiracy-curriosity about the 'Russian kid from Mars' ala an 'Indigo Child' and when back in the ~1990s or some time when he was interviewed, he was ~10 years old and he said that "Humans came from Mars, and after we got to earth, is when we started to age - because Earth is oxigen based, and breathing oxygen is what makes you age." And this crazy piece talks about the iron found in the martian atmosphere: http://www.nuclearplanet.com/Martian%20Iron.html http://www.nuclearplanet.com/Martian%20Iron.html >>The atmosphere of Mars is 95.7% carbon dioxide (CO2), which is available everywhere at the surface and which can readily be compressed. The Martian carbon dioxide can be, simultaneously, a source of carbon monoxide (CO) and a source of oxygen (O2) through the thermal decomposition reaction: >>*2 CO2 → 2 CO + O2 (20.2)* >>Reaction Eq. (20.2) requires a temperature of about 1100C. Note that the iron reduction reaction Eq. (20.1) can take place at about 700C, but a higher temperature, such as 900C, would be desirable. --- What happens if a Nuke goes off in the Martian atmosphere?