4 ms·

Cholecystectomies can also be performed in cases of cholecystitis (inflammation of the gallbladder) which can of course be caused by gallstones but also by infe

Cholecystectomies can also be performed in cases of cholecystitis (inflammation of the gallbladder) which can of course be caused by gallstones but also by infections of the bile tract, reduced blood flow to the gallbladder and other nasty things like tumors. Not sure how exactly this product caused the inflammation though..

_benedict 4y ago
Also anything that affects gut motility, so anything that messes with the nervous system in the gut. If the signalling controlling eg the sphincter is messed up, the bile won’t escape to the intestines, and if the bile stops flowing you’ll get liver and pancreatic inflammation. It might be that some toxin in the food could cause such an effect? I’m not sure how easy it would be to tell if this was the case in an acute setting though. It isn’t exactly common, and is usually chronic and intermittent. Gall bladder removal would seem to be the wrong treatment in this case, but it might be hard to establish? My amateur medical knowledge is insufficient to know, just hypothesising other potential mechanisms.
- decebalus1 4y ago
  You're spot on about bile not flowing. I'm very interested in the final verdict on this. I'm also not an expert, just someone who parted with their gallbladder a while back and became a major consumer of information on gallbladder pathology.
Engineering-MD 4y ago
Acalculi cholecystitis (cholecystitis not caused by gallstones) is rarely treated with surgery, it is usually just antibiotics. Cholecystectomies are indicated in cholecystitis, gallbladder tumours and gallbladder perforations (rare).
- decebalus1 4y ago
  Is it possible that these people already had asymptomatic gallstones and whatever was in this food triggered a gallbladder attack?
  - Engineering-MD 4y ago
    While certain foods (high fat content) can trigger biliary colic, I’m not aware of any specific foods that would trigger this more than any other with a similar fat content

_benedict 4y ago

Also anything that affects gut motility, so anything that messes with the nervous system in the gut. If the signalling controlling eg the sphincter is messed up, the bile won’t escape to the intestines, and if the bile stops flowing you’ll get liver and pancreatic inflammation. It might be that some toxin in the food could cause such an effect? I’m not sure how easy it would be to tell if this was the case in an acute setting though. It isn’t exactly common, and is usually chronic and intermittent. Gall bladder removal would seem to be the wrong treatment in this case, but it might be hard to establish? My amateur medical knowledge is insufficient to know, just hypothesising other potential mechanisms.

decebalus1 4y ago
You're spot on about bile not flowing. I'm very interested in the final verdict on this. I'm also not an expert, just someone who parted with their gallbladder a while back and became a major consumer of information on gallbladder pathology.

Engineering-MD 4y ago

Acalculi cholecystitis (cholecystitis not caused by gallstones) is rarely treated with surgery, it is usually just antibiotics. Cholecystectomies are indicated in cholecystitis, gallbladder tumours and gallbladder perforations (rare).

decebalus1 4y ago
Is it possible that these people already had asymptomatic gallstones and whatever was in this food triggered a gallbladder attack?
- Engineering-MD 4y ago
  While certain foods (high fat content) can trigger biliary colic, I’m not aware of any specific foods that would trigger this more than any other with a similar fat content