Society works on a handshake; there is no ultimate moral arbiter. So when the vast majority agree that certain words are no longer offensive, then it's OK to us

Society works on a handshake; there is no ultimate moral arbiter. So when the vast majority agree that certain words are no longer offensive, then it's OK to use them without concern. However, as long as that isn't the case (and it certainly is not the case in general in most societies at this time) you have to consider more than just your own personal views on profanity. If you are offending a portion of your audience, then it's fair to say that you're being disrespectful to hat portion of the audience. Most people I know use profanity (sparingly) with their peers (age-wise), very rarely with their parents, and almost never with their grandparents or young children. I think that reflects a knowledge of their audience and a respect for varying levels of tolerance to profanity. I find it troubling when I encounter people that lack that level of respect for others, and shameful when I'm guilty of it myself. Broadcasting something on a very public medium like the internet means you can't possibly predict your audience and therefore can't really determine whether profanity will be offensive or not. So why not refrain.