4 ms·
Exposing SARS-CoV-2 to low doses of nirmatrelvir (active ingredient in Paxlovid) generates resistant strains. The preprints: https://www.biorxiv.org/content/10
by Metacelsus 4y ago
Exposing SARS-CoV-2 to low doses of nirmatrelvir (active ingredient in Paxlovid) generates resistant strains.
The preprints: https://www.biorxiv.org/content/10.1101/2022.06.06.494921v1.full https://www.biorxiv.org/content/10.1101/2022.06.06.494921v1.... and https://www.biorxiv.org/content/10.1101/2022.06.07.495116v1.full https://www.biorxiv.org/content/10.1101/2022.06.07.495116v1....
But did we really need to do these experiments? It seems very foolish to intentionally generate these resistance mutations.
- atoav 4y agoThere are a lot of things that are foolish if there is no safety in place. I guess the number of risk assessments that have to be done for such a thing are higher than what we know from our jobs.