I suspect you may be right. Many supplements that have been tried just get broken down in digestion and don't actually increase target levels in the target tiss

I suspect you may be right. Many supplements that have been tried just get broken down in digestion and don't actually increase target levels in the target tissues, rather we need to find ways of increasing the intake of precursor or figuring out which microbiota are involved in the metabolism and giving them a helping hand or just adding them altogether